Opinion - Journal of Apitherapy (2022)
Royal Jelly: A Traditional Medicine and its Commercial Uses
Aishah Albalawi*Aishah Albalawi, Department of Applied Science, Umm Al-Qura University, Makkah, Saudi Arabia, Email: drstangaciu@gmail.com
Received: 02-May-2022, Manuscript No. JAPITHERAPY-22-68326; Editor assigned: 04-May-2022, Pre QC No. JAPITHERAPY-22-68326 (PQ); Reviewed: 19-May-2022, QC No. JAPITHERAPY-22-68326; Revised: 24-May-2022, Manuscript No. JAPITHERAPY-22-68326 (R); Published: 02-Jun-2022
Description
A milky-white substance made by worker bees called royal jelly aids in the growth of the queen bee. Apis mellifera, Bee Saliva, Bee Spit, Gelée Royale, Honey Bee Milk, Honey Bee’s Milk, Jalea Real, Lait des Abeilles, or Royal Bee Jelly are other names for royal jelly. Due to its remarkable properties, this natural product has been regarded throughout history as a gold mine for both conventional and alternative medicine. Commercial medical items have long contained royal jelly [1]. It has been shown to have a wide range of functional qualities, including antioxidant, antibacterial, anti-inflammatory, vasodilator, hypotensive, anticancer, and estrogen-like properties. Common uses for this substance include treating conditions like diabetes, cancer, Alzheimer’s disease, sexual dysfunction, and cardiovascular disease. The major goal of this study is to demonstrate how well royal jelly supplements can treat problems associated with ageing and menopause [2]. The worldwide healthcare system has struggled greatly with the problem of non-healing wounds. Unfortunately, royal jelly, a traditional treatment for a variety of skin injuries, has not been utilised frequently in clinical settings for cutaneous wounds [3]. This may be because of misunderstandings and a lack of information regarding the effectiveness of various types of royal jelly, its bioactive components, and the precise mechanisms underlying its wound-healing properties [4]. This medication has a unique ingredient called 10- HDA in particular. Due to traditional medicine and apitherapy, Royal jelly has historically been used as a health enhancer and is currently quite relevant in China. Due to its health-promoting qualities, it is now primarily consumed as a functional food or included in supplements and other formulations [5]. Royal jelly or its particular components have been shown to have anti-lipidemic, antioxidant, antiproliferative, antibacterial, neuroprotective, anti-inflammatory, immunomodulatory, antiaging, and estrogenic properties [6]. The hypopharyngeal and mandibular glands of nursing bees secrete royal jelly, a yellowish-white, acidic substance that is fed to developing worker larvae during the first three days and for the duration of the queen bee’s life. Royal Jelly is a highly regarded and cherished natural product that has been used for a very long time in traditional medicines, health foods, and cosmetics around the world. In order to understand its bioactivities, including its antibacterial, antioxidant, anti-aging, immunomodulatory, and general tonic activity against laboratory animals, microbiological organisms, farm animals, and clinical trials, it is also the most researched bee product. Numerous illnesses, such as cancer, diabetes, cardiovascular disease, and Alzheimer’s disease, are frequently treated with it. The natural bee product known as royal jelly possesses physiologically active components that have anticancer, antiallergic, antibacterial, and immune-regulating properties. Abdominal pain and diarrhoea may be symptoms of Inflammatory Bowel Disease (IBD), a chronic inflammatory condition of the intestines. With this research, we aimed to investigate RJ’s protective effects on mice with colitis brought on by DSS [7]. The RJ samples utilised in this study’s physiochemical analysis complied with both international and Chinese national standards. The Hypopharyngeal Glands (HGs) of honeybee workers secrete royal jelly. A population of honeybees chosen from Italian Bees (ITBs) known as high Royal Jelly producing Bees (RJBs) has evolved a better capacity to make RJ than ITBs. However, nothing is currently known about the mechanism underlying the strong RJ-producing performance in RJBs. We have thoroughly described and contrasted the proteome of worker bees from ITBs and RJBs over the course of their lifespans [8]. Our findings reveal unique molecular environments that control gland development and function in accordance with age-specific activities. To fuel the gland activities of RJ secretion, Nurse Bees (NBs) have well-developed acini shape and cytoskeleton of secretory cells in HGs.
References
- Stocker A, Schramel P, Kettrup A, Bengsch E. Trace and mineral elements in royal jelly and homeostatic effects. J Trace Elem Med Biolm 2005;
[PubMed] [CrossRef] [Google Scholar]
- Nakajima Y, Tsuruma K, Shimazawa M, Mishima S, Hara H. Comparison of bee products based on assays of antioxidant capacities. BMC Complement Altern Med 2009; 9:4.
[Crossref] [Google scholar] [Pubmed]
- Wang X, Sankarapandian K, Cheng Y, Woo SO, Kwon HW, Perumalsamy H, et al. Relationship between total phenolic contents and biological properties of propolis from 20 different regions in South Korea. BMC Complement Altern Med 2016; 16:65.
[Crossref] [Google scholar] [Pubmed]
- Kocot J, Kiełczykowska M, Luchowska-Kocot D, Kurzepa J, Musik I. Antioxidant Potential of Propolis, Bee Pollen, and Royal Jelly: Possible Medical Application. Oxid Med Cell Longev 2018.
[Crossref] [Google scholar] [Pubmed]
- Wang H, Khor TO, Shu L, Su Z, Fuentes F, Lee J-H, et al. Plants against cancer: A review on natural phytochemicals in preventing and treating cancers and their druggability. Anticancer Agents Med Chem 2012; 12:1281–1305.
[Crossref] [Google scholar] [Pubmed]
- Ahn M-R, Kunimasa K, Ohta T, Kumazawa S, Kamihira M, Kaji K, et al. Suppression of tumor-induced angiogenesis by Brazilian propolis: Major component artepillin C inhibits in vitro tube formation and endothelial cell proliferation. Cancer Lett 2007; 252:235–243.
[Crossref] [Google scholar] [Pubmed]
- Sawicka D, Car H, Borawska MH, Nikliński J. The anticancer activity of propolis. Folia Histochem Cytobiol 2012; 50:25–37.
[Crossref] [Google scholar] [Pubmed]
- Marcucci MC. Propolis: chemical composition, biological properties and therapeutic activity. Apidologie 1995; 26:83–99.
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