E-ISSN 2474-137X
 

Original Research (Original Article) 


Comparison of efficacy of Natural honey and Triamcinolone acetonide (0.1%) in the healing of oral ulcers- A clinical study

Dr.Supriya Vijay Gupta, Dr.Vidya krushnarao Lohe, Dr.Rahul Raghunath Bhowate.

Abstract
BACKGROUND: To compare the effectiveness of Natural Honey with Triamcinolone acetonide (0.1%) on the healing of Oral ulcers. METHODS: Seventy four oral ulcers (forty nine recurrent aphthous stomatitis, sixteen aphthous like ulcers in Oral submucous fibrosis and nine traumatic ulcers) were evaluated and each half of them were advised to apply honey and triamcinolone acetonide. Pain score (visual analog scale), ulcer size (measured by William’s Periodontal Probe), erythema level was evaluated on first day and after drug application. Statistical Analysis was done and tabulated by SPSS software. RESULTS: Natural honey showed significant reduction in pain score and ulcer size (p<0.05) as compared to triamcinolone acetonide on third day. There was similar reduction in erythema level (p<0.05) in both groups. Natural honey showed significant reduction in moderating pain in recurrent aphthous stomatitis and aphthous like ulcers in oral submucous fibrosis where as insignificant reduction in ulcer size and erythema level in all the three subgroups. Also, Triamcinolone acetonide showed insignificant reduction in moderating pain, ulcer size and erythema level in all the subgroups of oral ulcers. CONCLUSION: The data clearly demonstrate that with the use of honey, no allergic reaction elicited and no significant side effects were reported. In addition to its valuable nutritional constituents, honey has anti-inflammatory, antioxidant activities that make it a suitable natural subject for healing oral ulcers. Thus, it might help clinicians to give alternative treatment of oral ulcers for their patients since honey is worldwide available and cheaperreadily available across the globe.

Key words: Natural Honey, Triamcinolone acetonide, Recurrent Aphthous Stomatitis, Traumatic Ulcer, Aphthous like Ulcers in Oral submucous fibrosis.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Dr.Supriya Vijay Gupta
Articles by Dr.Vidya krushnarao Lohe
Articles by Dr.Rahul Raghunath Bhowate
on Google
on Google Scholar
Article Statistics
 Viewed: 3658
Downloaded: 1238
Cited: 0


How to Cite this Article
Pubmed Style

Dr.Supriya Vijay Gupta, Dr.Vidya krushnarao Lohe, Dr.Rahul Raghunath Bhowate. Comparison of efficacy of Natural honey and Triamcinolone acetonide (0.1%) in the healing of oral ulcers- A clinical study. J Apither. 2018; 3(1): 1-8. doi:10.5455/ja.20170304121448


Web Style

Dr.Supriya Vijay Gupta, Dr.Vidya krushnarao Lohe, Dr.Rahul Raghunath Bhowate. Comparison of efficacy of Natural honey and Triamcinolone acetonide (0.1%) in the healing of oral ulcers- A clinical study. http://www.japitherapy.com/?mno=260402 [Access: November 17, 2019]. doi:10.5455/ja.20170304121448


AMA (American Medical Association) Style

Dr.Supriya Vijay Gupta, Dr.Vidya krushnarao Lohe, Dr.Rahul Raghunath Bhowate. Comparison of efficacy of Natural honey and Triamcinolone acetonide (0.1%) in the healing of oral ulcers- A clinical study. J Apither. 2018; 3(1): 1-8. doi:10.5455/ja.20170304121448



Vancouver/ICMJE Style

Dr.Supriya Vijay Gupta, Dr.Vidya krushnarao Lohe, Dr.Rahul Raghunath Bhowate. Comparison of efficacy of Natural honey and Triamcinolone acetonide (0.1%) in the healing of oral ulcers- A clinical study. J Apither. (2018), [cited November 17, 2019]; 3(1): 1-8. doi:10.5455/ja.20170304121448



Harvard Style

Dr.Supriya Vijay Gupta, Dr.Vidya krushnarao Lohe, Dr.Rahul Raghunath Bhowate (2018) Comparison of efficacy of Natural honey and Triamcinolone acetonide (0.1%) in the healing of oral ulcers- A clinical study. J Apither, 3 (1), 1-8. doi:10.5455/ja.20170304121448



Turabian Style

Dr.Supriya Vijay Gupta, Dr.Vidya krushnarao Lohe, Dr.Rahul Raghunath Bhowate. 2018. Comparison of efficacy of Natural honey and Triamcinolone acetonide (0.1%) in the healing of oral ulcers- A clinical study. Journal of Apitherapy, 3 (1), 1-8. doi:10.5455/ja.20170304121448



Chicago Style

Dr.Supriya Vijay Gupta, Dr.Vidya krushnarao Lohe, Dr.Rahul Raghunath Bhowate. "Comparison of efficacy of Natural honey and Triamcinolone acetonide (0.1%) in the healing of oral ulcers- A clinical study." Journal of Apitherapy 3 (2018), 1-8. doi:10.5455/ja.20170304121448



MLA (The Modern Language Association) Style

Dr.Supriya Vijay Gupta, Dr.Vidya krushnarao Lohe, Dr.Rahul Raghunath Bhowate. "Comparison of efficacy of Natural honey and Triamcinolone acetonide (0.1%) in the healing of oral ulcers- A clinical study." Journal of Apitherapy 3.1 (2018), 1-8. Print. doi:10.5455/ja.20170304121448



APA (American Psychological Association) Style

Dr.Supriya Vijay Gupta, Dr.Vidya krushnarao Lohe, Dr.Rahul Raghunath Bhowate (2018) Comparison of efficacy of Natural honey and Triamcinolone acetonide (0.1%) in the healing of oral ulcers- A clinical study. Journal of Apitherapy, 3 (1), 1-8. doi:10.5455/ja.20170304121448





Most Viewed Articles
  • Welcome to Journal of Apitherapy
    Editor
    J Apither. 2016; 1(1): 1-1
    » Abstract & References » doi: 10.5455/ja.20160509012435

  • Honey and its uses in oral diseases- An overview
    Santosh R Patil, Ravi Kumar Gudipaneni
    J Apither. 2016; 1(1): 17-19
    » Abstract & References » doi: 10.5455/ja.20160428110757

  • The value of Mountain Sidr Honey in treating and controlling chronic constipation: A Prospective comparative study between Ziziphus honey and Lactulose in 1000 Saudi Arabian patients
    Bader Hamza Shirah, Hamza Asaad Shirah
    J Apither. 2016; 1(1): 2-6
    » Abstract & References » doi: 10.5455/ja.20160507094522

  • Wound healing with Apitherapy: A Review of the Effects of Honey
    Michael Malone, Gary Tsai
    J Apither. 2016; 1(1): 29-32
    » Abstract & References » doi: 10.5455/ja.20160620031837

  • Study on antibacterial efficacy of different honey types in South Western Nigeria against wound associated bacteria
    Rasheed Omotayo Adeyemo, Nkem Torimiro, Saheed Adekunle Akinola, Sodiq Kolawole Lawal, Tesleem Olatunde Abolarinwa, Wasiu Olalekan Adewoye
    J Apither. 2017; 2(1): 15-19
    » Abstract » doi: 10.5455/ja.20170309062135

  • Health Benefits and Traditional Uses of Honey: A Review
    Menuka - Arawwawala, sujatha - Hewageegana
    J Apither. 2017; 2(1): 9-14
    » Abstract » doi: 10.5455/ja.20170208043727

  • Propolis as an alternative in prevention and control of dental cavity
    Bárbara Soares Machado, Tarcyane Neves Pulcino, Ayalla Lima Silva, Diego Tadeu Melo, Renata Gomes Silva, Izabel Gomes Mendonça
    J Apither. 2016; 1(2): 47-50
    » Abstract » doi: 10.5455/ja.20160726115117

  • Extraction and analysis of biologically active compounds in different Algerian honeys
    Hamza Belkhodja, Asmaa Belmimoun, Boumediene Meddah
    J Apither. 2016; 1(1): 14-16
    » Abstract & References » doi: 10.5455/ja.20160507094104

  • Evaluate the cytotoxic activity of honey, propolis, and bee venom from different localities in Egypt against liver, breast, and colorectal cancer
    Farid Abd-Elrehim Abd-elaziz Badria, Hassan Mohamed Fathy, Ashraf Sherif Fatehe, Diaaeldin Mohamed Abdelkawi Elimam, Mohamed Ghazy Mohamed Ghazy
    J Apither. 2017; 2(1): 1-8
    » Abstract » doi: 10.5455/ja.20170203075953

  • Alteration of PUMA gene expression in mice by royal jelly and green tea.
    Wael S. Abdel-Mageed, Rasha Fathy, Mohamed Othman
    J Apither. 2016; 1(1): 7-13
    » Abstract & References » doi: 10.5455/ja.20160504095722

  • Most Downloaded
  • Health Benefits and Traditional Uses of Honey: A Review
    Menuka - Arawwawala, sujatha - Hewageegana
    J Apither. 2017; 2(1): 9-14
    » Abstract » doi: 10.5455/ja.20170208043727

  • The effects of honey supplementation on Egyptian children with hepatitis A: A randomized double blinded placebo controlled pilot study
    Mamdouh Abdulmaksoud Abdulrhman, Rania Shatla, Sahar Mohamed
    J Apither. 2016; 1(1): 23-28
    » Abstract & References » doi: 10.5455/ja.20160702011113

  • Wound healing with Apitherapy: A Review of the Effects of Honey
    Michael Malone, Gary Tsai
    J Apither. 2016; 1(1): 29-32
    » Abstract & References » doi: 10.5455/ja.20160620031837

  • The value of Mountain Sidr Honey in treating and controlling chronic constipation: A Prospective comparative study between Ziziphus honey and Lactulose in 1000 Saudi Arabian patients
    Bader Hamza Shirah, Hamza Asaad Shirah
    J Apither. 2016; 1(1): 2-6
    » Abstract & References » doi: 10.5455/ja.20160507094522

  • Welcome to Journal of Apitherapy
    Editor
    J Apither. 2016; 1(1): 1-1
    » Abstract & References » doi: 10.5455/ja.20160509012435

  • Evaluate the cytotoxic activity of honey, propolis, and bee venom from different localities in Egypt against liver, breast, and colorectal cancer
    Farid Abd-Elrehim Abd-elaziz Badria, Hassan Mohamed Fathy, Ashraf Sherif Fatehe, Diaaeldin Mohamed Abdelkawi Elimam, Mohamed Ghazy Mohamed Ghazy
    J Apither. 2017; 2(1): 1-8
    » Abstract » doi: 10.5455/ja.20170203075953

  • Honey and its uses in oral diseases- An overview
    Santosh R Patil, Ravi Kumar Gudipaneni
    J Apither. 2016; 1(1): 17-19
    » Abstract & References » doi: 10.5455/ja.20160428110757

  • Comparison of efficacy of Natural honey and Triamcinolone acetonide (0.1%) in the healing of oral ulcers- A clinical study
    Dr.Supriya Vijay Gupta, Dr.Vidya krushnarao Lohe, Dr.Rahul Raghunath Bhowate
    J Apither. 2018; 3(1): 1-8
    » Abstract » doi: 10.5455/ja.20170304121448

  • Treatment of Rhinosinusitis and Dry Eye with an Antibacterial Honey Nasal Spray
    Anita Perng, Julie Albietz, Kara Fung, Sheng Ho, Kevin Le, Katrina Leanne Schmid
    J Apither. 2016; 1(2): 36-42
    » Abstract » doi: 10.5455/ja.20160903114837

  • Study on antibacterial efficacy of different honey types in South Western Nigeria against wound associated bacteria
    Rasheed Omotayo Adeyemo, Nkem Torimiro, Saheed Adekunle Akinola, Sodiq Kolawole Lawal, Tesleem Olatunde Abolarinwa, Wasiu Olalekan Adewoye
    J Apither. 2017; 2(1): 15-19
    » Abstract » doi: 10.5455/ja.20170309062135

  • Most Cited Articles
  • Wound healing with Apitherapy: A Review of the Effects of Honey
    Michael Malone, Gary Tsai
    J Apither. 2016; 1(1): 29-32
    » Abstract & References » doi: 10.5455/ja.20160620031837
    Cited : 4 times [Click to see citing articles]

  • Propolis as an alternative in prevention and control of dental cavity
    Bárbara Soares Machado, Tarcyane Neves Pulcino, Ayalla Lima Silva, Diego Tadeu Melo, Renata Gomes Silva, Izabel Gomes Mendonça
    J Apither. 2016; 1(2): 47-50
    » Abstract » doi: 10.5455/ja.20160726115117
    Cited : 3 times [Click to see citing articles]

  • Evaluate the cytotoxic activity of honey, propolis, and bee venom from different localities in Egypt against liver, breast, and colorectal cancer
    Farid Abd-Elrehim Abd-elaziz Badria, Hassan Mohamed Fathy, Ashraf Sherif Fatehe, Diaaeldin Mohamed Abdelkawi Elimam, Mohamed Ghazy Mohamed Ghazy
    J Apither. 2017; 2(1): 1-8
    » Abstract » doi: 10.5455/ja.20170203075953
    Cited : 2 times [Click to see citing articles]

  • Meaningfulness of Apitherapeutic Approaches Using the Example of Primary Dysmenorrhoea
    Karsten Münstedt
    J Apither. 2018; 3(1): 9-16
    » Abstract » doi: 10.5455/ja.20170917090943
    Cited : 2 times [Click to see citing articles]

  • Honey and its uses in oral diseases- An overview
    Santosh R Patil, Ravi Kumar Gudipaneni
    J Apither. 2016; 1(1): 17-19
    » Abstract & References » doi: 10.5455/ja.20160428110757
    Cited : 1 time [Click to see citing article]

  • Honey in oral diseases: Ayurvedic and Unani perspective
    Arpita Rai
    J Apither. 2016; 1(2): 55-56
    » Abstract » doi: 10.5455/ja.20160606123350
    Cited : 1 time [Click to see citing article]

  • Caffeic Acid Phenethyl Ester (CAPE) Suppresses Systemic Inflammation In Rat Trauma Model
    İhsan Karaboğa
    J Apither. 2018; 3(2): 31-35
    » Abstract » doi: 10.5455/ja.20180702102008
    Cited : 1 time [Click to see citing article]

  • The effects of honey supplementation on Egyptian children with hepatitis A: A randomized double blinded placebo controlled pilot study
    Mamdouh Abdulmaksoud Abdulrhman, Rania Shatla, Sahar Mohamed
    J Apither. 2016; 1(1): 23-28
    » Abstract & References » doi: 10.5455/ja.20160702011113
    Cited : 1 time [Click to see citing article]

  • Melittin and Cancer
    Anna Tacón, Ph.D.
    J Apither. 2016; 1(2): 51-54
    » Abstract » doi: 10.5455/ja.20161027091813
    Cited : 1 time [Click to see citing article]

  • Health Benefits and Traditional Uses of Honey: A Review
    Menuka - Arawwawala, sujatha - Hewageegana
    J Apither. 2017; 2(1): 9-14
    » Abstract » doi: 10.5455/ja.20170208043727
    Cited : 1 time [Click to see citing article]